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Ivermectin, also known as Stromectol, is an antiparasitic drug used by people and animals alike. It's an antiparasitic with a broad spectrum of effects that may be used to treat a variety of conditions. It was recently added to the World Health Organization's (WHO) list of essential medications. Ivermectin belongs to the Anthelmintic class of antiparasitic medications, which shock or kill parasitic worms or internal parasites without harming the host.In veterinary medicine, these pills are used to treat ascariasis (a mite infestation) and animal heartworms. Ivermectin 12 mg is used to treat parasitic illnesses such as head lice and scabies in humans. Strongyloidiasis, a roundworm infection, and river blindness, a parasitic condition caused by the worm Onchocerca Volvulus, both require this medicine. It's also used to treat heartworm and whipworm infections, as well as lymphatic filariasis, a worm-borne illness that affects humans.
Ivermectin kills parasites by triggering the release of an excessive amount of neurotransmitters in the parasite's peripheral nervous system. It works by paralyzing the parasite's body, leaving it ineffective and killing the larvae, allowing them to be rapidly and efficiently removed from the host. Ivermectin is thought to bind to proteins generated by juvenile worms, suppressing the host's immune system and allowing white blood cells to destroy the worms after the host's immune system has recovered. Adult worms' development is also slowed, reducing their symptomatic impact on the body.
The dosage of this medicine is determined by the patient's weight as well as the illness being treated. Ivermectin is most typically used as a cream, but it's also available as oral pills that take a bit longer to function or as a subcutaneous injection that works significantly faster. Maximum Ivermectin levels are normally obtained within 2-5 hours after administration. It has an 18-hour half-life and is primarily eliminated in the feces, with a tiny quantity remaining in the urine. It's vital to note that, although having a large impact on parasites in the human body, it doesn't penetrate the blood-brain barrier, making it a highly safe pharmaceutical option.
To treat the condition more successfully, it is critical to learn how to use Ivermectin appropriately. Ivermectin pills should be taken once a day with a full glass of water. The dose should be taken around an hour before breakfast in the morning. Depending on the severity of the illness and the practitioner's treatment method, the dose is usually repeated every 6-12 months. In those with Onchocerciasis or river blindness, a corticosteroid is given in addition to Ivermectin to alleviate the pain produced by the worms' death. In adults, teens, and children weighing more than 15kg, river blindness is treated with 150mcg per kg.
The adverse effects of Ivermectin are mostly dictated by the condition for which it is given. Fever, itching, and skin rashes are all adverse effects of Ivermectin therapy for Onchocerciasis, as are swollen glands in the neck and armpits. Swelling of the hands, feet, legs, and face, as well as headaches and a fast pulse, are all symptoms that might occur. You may have tiredness and lightheadedness, as well as lack of appetite and shivering and trembling emotions when attempting to get up after taking Strongyloidiasis medication for skin rashes, dizziness, or diarrhea. Steven-Johnson syndrome and bronchial asthma have been linked to other Ivermectin adverse effects.
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