Topic: finasteride

The currently recommended therapy for female pattern hair loss (FPHL) is topical minoxidil administration; however, in some individuals, this medication does not result in hair regrowth. Finasteride, a selective 5-reductase inhibitor (5-ARI), might be an alternate therapy. However, due to the possibility of teratogenic consequences, clinical trials and usage of Propecia for women are constrained. The goal of this review is to summarize the literature on the pharmacology, clinical efficacy, an...

Hvilken rolle spiller testosteron/hormoner/androgener i mandligt hårtab? Mandligt hårtab, eller androgenetisk alopeci, er en androgenafhængig lidelse. Hos genetisk modtagelige mænd bidrager dihydrotestosteron (DHT), en potent metabolit af det mandlige androgen testosteron, til hårtab hos mænd. Omdannelsen af ​​testosteron til DHT reguleres af enzymet 5-alfa-reduktase. Hvordan påvirker finasterid kroppens hormonelle/endokrine system? Finasteride (Propecia® og andre) er en specifik type I...